Healthy physiologic function is characterized by a complex interaction of multiple control mechanisms that enable an individual to adapt to the exigencies and unpredictable changes of everyday life (2, 3). As implied by its name, non-linear dinamics studies systems, such as those in  physiology, in wich out-put is not proportional to in-put. Physiologic processes show highly variable fluctuations resembling “chaos”. The term “chaos” describes an apparently unpredictable behaviour that may arise from the internal feed-back loops of certain non-linear systems.

         This healthy variability is not just random, uncontrolled fluctuations, however. Allthough the precise mathematical definition of “chaos” is somewhat complicated, its presence in the body can be characterized by two things: first, it is there by design, for instance it is not caused by the random firing of neurons; second, the behaviour of a chaotic system is complicated and unpredictable.

         As a matter of facts, vasomotility and vasomotion of every tissue-microvascular-unit physiolocically show an highly  complex type of variability, “constrained randomnes”, reminescent of “chaos”, which may be evaluated at the bed-side with the aid of a new physical semeiotics, Biophysical Semeiotics, as we demonstated previously (2, 3) for the first time clinically, by mean of numerous ureteral reflexes.

Biophysical Semeiotics, based upon Auscultatory Percussion and the so-called Auscultatory Percussion-Reflex-Diagnostic, studies these non-linear dinamics of all biological systems.

In Auscultatory Percussion as well as A.P. Reflex-Diagnostic and consequently in the new, original semeiotics, auscultatory percussion of the stomach plaies a primary role. Notoriously, the stomach is ruled by upper and lower neuronal plexus, that are in direct relation with  celiac plexus, in which bring to an end numerous reflexes, caused by trigger-points stimulation of allmost every tissue. Therefore, doctor who will learn Biophysical Semeiotics has to study, first of all, this application, that allows him to recognize clinically, for instance, promptly and easy, an acute or chronic appendicitis , indipendently from its location and/or seriousness. (See Appendicite on Home-Page)



1.     Stagnaro-Neri M., Stagnaro S., Appendicite. Min. Med. 87, 183


2.     Stagnaro-Neri M., Stagnaro S., Deterministic Chaos, Preconditioning and Myocardial Oxygenation evaluated clinically with the aid of Biophysical Semeiotics in the Diagnosis of ischaemic Heart Disease even silent. Acta Med. Medit. 13, 109



3.     Stagnaro-Neri M., Stagnaro S., Deterministic chaotic biological system: the microcirculatory bed. Theoretical and practical aspects. Gazz. Med. It. – Arch. Sc. Med. 153, 99  


                 Last update: March 18, 2018